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BIO 460
Evolution

Faculty Faculty of Engineering and Natural Sciences
Semester Spring 2025-2026
Course BIO 460 - Evolution
Time/Place
Time
Week Day
Place
Date
11:40-12:30
Thu
FENS-L047
Feb 16-May 22, 2026
09:40-11:30
Fri
FENS-L061
Feb 16-May 22, 2026
Level of course Undergraduate
Course Credits SU Credit:3, ECTS:6, Basic:6
Prerequisites -
Corequisites -
Course Type Lecture

Instructor(s) Information

Ogün Adebali

Course Information

Catalog Course Description
The course begins by introducing the foundational concepts of evolutionary biology in Unit I: An Idea that Changed the World. Students will explore the historical development of evolutionary thought, beginning with pre-Darwinian ideas and moving through Darwin's contributions to the Modern Synthesis. This unit also introduces the construction and interpretation of phylogenetic trees as tools for understanding evolutionary relationships. In Unit II: How Evolution Works, the course examines the fundamental mechanisms of evolution. Topics include the origins of genetic variation through mutation and recombination, and the population-level processes of natural selection, genetic drift, and gene flow. Students will learn how these forces interact to shape allele frequencies and phenotypic traits across generations, supported by population genetics models and equilibrium theory. Unit III: The Products of Evolution focuses on the processes that generate biological diversity. Students will study the definition and formation of species, mechanisms of reproductive isolation, and modes of speciation. Additionally, this unit introduces evolutionary developmental biology (Evo-Devo), exploring how genetic and regulatory changes lead to morphological innovation and complexity. In Unit IV: Interactions Between Individuals and Species, the course delves into the evolutionary consequences of social and ecological interactions. Topics include sexual selection and the evolution of mating strategies, kin selection, altruism, and the emergence of cooperation. Students will also examine how interspecies dynamics such as predation, mutualism, and coevolution drive evolutionary change. Unit V: The History of Life provides a macroevolutionary perspective, tracing the deep history of life on Earth. Students will learn about the Tree of Life, major evolutionary transitions (such as multicellularity and terrestrialization), and adaptive radiations. The unit also explores mass extinctions and how they have shaped the diversity of life through macroevolutionary processes. Finally, Unit VI: Evolution of Homo sapiens addresses human evolution from an evolutionary biology perspective. Students will study the fossil and genetic evidence for human origins, population divergence, and adaptation. This unit also introduces concepts in evolutionary medicine and discusses how evolutionary theory applies to health, disease, and ethics in modern society.
Course Learning Outcomes:
1. Conceptual Understanding of Evolutionary Theory; ? Explain fundamental principles of evolutionary biology, including descent with modification, common ancestry, and natural selection. ? Differentiate between microevolution (small-scale genetic changes within populations) and macroevolution (large-scale changes leading to speciation and extinction). ? Analyze historical perspectives on evolution, from Darwin?s contributions to modern evolutionary synthesis, and evaluate how evolutionary thought has advanced over time. ? Apply evolutionary reasoning to explain biodiversity, adaptation, and the origins of complex traits.
2. Evolutionary Mechanisms and Genetic Foundations; ? Describe how genetic variation arises through mutations, recombination, gene flow, and horizontal gene transfer. ? Understand Hardy-Weinberg equilibrium and how deviations from it indicate evolutionary forces at work. ? Apply population genetics models to explain how natural selection, genetic drift, and gene flow shape genetic diversity. ? Interpret fitness landscapes and their role in adaptive evolution and speciation? Analyze genome evolution, including how gene duplication, exon shuffling, and transposable elements contribute to evolutionary innovation.
3. Evolutionary Processes at the Species and Population Levels? Explain the process of speciation, including allopatric, sympatric, and parapatric speciation. ? Distinguish between different species concepts, such as biological, morphological, and phylogenetic species definitions. ? Analyze the impact of geographic and ecological factors on evolutionary divergence and adaptation. ? Describe mechanisms of reproductive isolation and how they maintain species boundaries. ? Interpret phylogenetic trees and apply them to reconstruct evolutionary relationships.
4. Evolutionary Ecology and Behavior ? Explain how ecological interactions shape evolutionary trajectories, including predator-prey dynamics, competition, and mutualism. ? Analyze the role of sexual selection in shaping mating strategies, secondary sexual traits, and reproductive success. ? Evaluate cooperative and altruistic behaviors using kin selection, game theory, and inclusive fitness models. ? Understand life history evolution, including trade-offs in reproduction, survival, and aging.
5. Macroevolution and the History of Life ? Describe the major evolutionary transitions leading to the diversity of life on Earth. ? Explain the significance of mass extinctions and their role in shaping evolutionary trajectories. ? Analyze how fossils and molecular data are used to infer evolutionary histories. ? Understand how evolutionary developmental biology (Evo-Devo) explains the origins of novel structures and complexity. ? Use phylogenetic comparative methods to study trait evolution across species.
6. Evolutionary Medicine and Human Evolution ? Explain the evolutionary origins of Homo sapiens, including genetic and fossil evidence of human ancestry. ? Analyze how natural selection has shaped human physiology, including adaptations to diet, climate, and disease resistance. ? Apply evolutionary principles to medicine, including the emergence of antibiotic resistance, cancer evolution, and host-pathogen interactions. ? Understand how genetic variation influences human traits, including complex diseases and behavioral evolution.
Course Objective
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Course Materials

Resources:
Futuyma, D.J., & Kirkpatrick, M. (2023). Evolution (5th edition). Oxford University Press
Technology Requirements:
Computers (or tablets) should be brought to the class to answer TopHat questions.

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