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MAT 516
Biomaterials Science and Biocompatibility

Faculty Faculty of Engineering and Natural Sciences
Semester Spring 2025-2026
Course MAT 516 - Biomaterials Science and Biocompatibility
Time/Place
Time
Week Day
Place
Date
15:40-16:30
Tue
FENS-L058
Feb 16-May 22, 2026
08:40-10:30
Fri
FENS-L065
Feb 16-May 22, 2026
Level of course Masters
Course Credits SU Credit:3, ECTS:10
Prerequisites -
Corequisites -
Course Type Lecture

Instructor(s) Information

Gözde İnce

Course Information

Catalog Course Description
Introduction to biomaterials science and biocompatibility. Structure and properties of tissues and cells. Surface properties of materials and characterization of biomaterials surfaces. Classes of materials used in medicine: Metals, polymers, hydrogels, bioresorbable materials, ceramics, glasses, composites, thin films, fabrics and biologically functional materials. Microscopic and macroscopic structure of tissue. Mechanical properties of tissue. Pathobiological responses to implants. Medical implant design and function. Application of materials in medicine and dentistry. Cardiovascular applications. Dental implants. Orthopaedic applications. Ophthalmologic applications. Sutures. Adhesives and sealants. Tissue engineering.
Course Learning Outcomes:
1. Upon successful completion of Biomaterials and Biocompatibility (MAT516), students are expected to: - Describe the principle types, structure, testing and properties of biomaterials, - Discuss the interplay between biomaterials and the body at various stages following contact/implantation, - Compare a normal implant healing process against adverse scenarios such as an allergic foreign body reaction, - List the preservation techniques of biomaterials - Discuss the potential of tissue engineering and the potential influence of physico-chemical-mechanical actuation on the state of an implanted scaffold
Course Objective
To understand the basic principles of biology and materials design (ceramics, polymers, metals, composites thereof), processing, testing, and characterization as is pertains to the immune response, foreign body reaction, healing versus infection & tissue engineering.
Sustainable Development Goals (SDGs) Related to This Course:
Good Health and Well-being
Industry, Innovation and Infrastructure

Course Materials

Resources:
I. Biomaterials, A Basic Introduction (Q. Chen, G. Thoukas)
II. Introduction to Biomaterials (Agrawal, Ong et al)
III. Biomaterials: An Introduction (Park, Lakes)
IV. Biomaterials Science (Ratner et al.)
V. Handbook of Biomaterial Properties (Murphy, Black et al.)
Technology Requirements:

Policies