This course will introduce advanced design and fabrication methodologies in development of customized medical devices and tools, implants, and engineered tissues, organs and biological systems. The topics covered include computer- aided design and representation of biological objects, computational geometry for medical imaging and processing, reverse engineering, computer-aided analysis and engineering, biomaterials, tissue engineering, additive manufacturing for biomedical engineering applications, bio- manufacturing and manufacturing processes for medical devices/tools. The course also includes several related hands-on laboratory projects.

To use advanced computer-aided design and fabrication technologies in development of biomedical related products such as customized medical devices, tools, implants, engineered tissues, organs and biological systems.
Outcomes: At the conclusion of this course, you will be able to:
- Understand and develop segmentation methods for medical images
- Model custom implants using medical images
- Analyze and optimize implants or medical devices based on biological and process requirements
- Develop and implement algorithms to model implants, medical devices, tissue scaffolds
- Decide on biomaterials for biomanufacturing
- Develop optimum plans for manufacturing of implants and medical devices and tissue engineering
- Develop bio manufacturing processes to produce custom implants, medical devices and tissue constructs.

References:
- Tissue Engineering by B. Palsson and S. N. Bhatia, Prentice Hall 2004
- Biomaterials, J.S. Temenoff and A. G. Mikos, Prentice Hall, 2008
- Advanced Manufacturing Technology for Medical Applications: Reverse Engineering, Software Conversion and Rapid Prototyping by Ian Gibson (Editor), Wiley, 2006.
- Computer Aided Manufacturing, by T.C. Chang, R.A. Wysk, and H.P. Wang 3rd Edition, Prentice Hall, 2006.
- Product Design: Techniques in Reverse Engineering and New Product Development by K. Otto and K. Wood, Prentice Hall, 2001.
- Principles of CAD/CAM/CAE, by K. Lee, Addison-Wesley, 1999.